Search on: OROTIDINE-5'-PHOSPHATE PYROPHOSPHORYLASE 
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Descriptor English:   Orotate Phosphoribosyltransferase 
Descriptor Spanish:   Orotato Fosforribosiltransferasa 
Descriptor Portuguese:   Orotato Fosforribosiltransferase 
Synonyms English:   Orotidine-5'-Phosphate Pyrophosphorylase
Orotidylic Acid Phosphorylase  
Tree Number:   D08.811.913.400.725.700
Definition English:   The enzyme catalyzing the formation of orotidine-5'-phosphoric acid (orotidylic acid) from orotic acid and 5-phosphoribosyl-1-pyrophosphate in the course of pyrimidine nucleotide biosynthesis. EC 2.4.2.10. 
Indexing Annotation English:   /defic: consider also OROTIC ACID /urine (IM) + PURINE-PYRIMIDINE METABOLISM, INBORN ERRORS (IM)
History Note English:   91(77); was see under PENTOSYLTRANSFERASES 1977-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   10140 
Unique Identifier:   D009962 

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